This prescription medication is a TNF blocking agent that works to reduce inflammation, thereby preventing further disease progression. This form of Simponi (50 mg solution for injection) is supplied in a pre-filled syringe for self-injection. Administration of Simponi should be conducted under the supervision of a healthcare professional.
What is it made of?
The active ingredient of Simponi is a protein (golimumab, 50 mg) with selective binding capability to TNF-alpha. Simponi also contains the inactive ingredients sorbitol, polysorbate 80, L-histidine, L-histidine monohydrochloride monohydrate, and water for injection.
What are its uses?
Simponi is used to treat inflammation-related conditions such as rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, ankylosing spondylitis, and non-radiographic axial spondyloarthritis in adults over 18 years of age. Simponi treatment is considered after first-line treatments, like methotrexate, have been attempted and shown to bring unsatisfactory results.
How long do its effects last?
Simponi confers effects as long as the patient continues to use the medication.