ACTEMRA® 400mg/20ml (Non-English)
400mg/20ml 1-20ml vial
Buy Actemra for patients suffering from rheumatoid arthritis. The medication, which has the generic name of tocilizumab, is also known as RoActemra, and is usually used to treat rheumatoid arthritis, as well as other ailments.
Who benefits the most from Actemra
This medicine is usually recommended for use on patients with rheumatoid arthritis, but it can be used to treat other diseases and symptoms.
Ailments Treated with Actemra
These are some of the ailments that Actemra is capable of treating:
- Rheumatoid arthritis
- Covid-19 (in adults receiving systemic corticosteroids that require supplemental oxygen or mechanical ventilation)
- Active systemic juvenile idiopathic arthritis
- Juvenile idiopathic polyarthritis (combined usually with methotrexate)
- Chimeric antigen receptor
- Life-threatening cytokine release syndrome
How does Actemra work?
Actemra contains the active ingredient tocilizumab is a kind of monoclonal antibody which is a kind of protein that was developed to target specific antigens in the body. This particular medication targets the receptor for a messenger molecule also known as a cytokine named interleukin-6. This cytokine is a part of what causes the inflammation in some diseases, and can be found in large amounts with rheumatoid arthritis, giant cell arteritis, and Covid-19. The solution attaches to the target receptors and will then cause a reduction in the inflammation the patient is experiencing, as well as other symptoms.
Actemra is often introduced via an injection under the skin or into a vein. The medicine is usually administered every one to four weeks, depending on the condition. For CRS, usually only one dose is given. When introduced into the vein, it happens over a period of about 1 hour. For every administration, another site must be targeted as not one site should be injected into twice in a row. For more information on dosing, please refer to the product leaflet.
How long does Actemra last?
For giant cell arteritis, this medication is used for up to 1 year usually. For CRS, it is only used for a short period of time, usually when symptoms are resolved at around 1 or 2 weeks. The duration is largely dependent on what kind of disease is being treated, and the full list of which can be found in the package insert.
Patients with hypersensitivities to any of Actemra’s components should avoid it. Those who have active infections, aside from Covid-19 should avoid using this as well.
Other Side Effects
These are signs of infections and if the patient has them, they should immediately call the doctor
- Severe stomach cramps or diarrhea
- Unusual bleeding
- Liver problems
- Signs of infection
- Signs of tuberculosis
- Signs of perforation in the stomach or intestine
Common side effects include:
- Increased blood pressure
- Runny or stuffy nose
- Sore throat
- Pain, swelling, burning
For a full list, please check the package leaflet.
Patients who are undergoing this treatment should avoid receiving any live vaccines, which include but are not limited to mumps, measles, rubella, rotavirus, yellow fever, typhoid, shingles, and chickenpox. Patients should also avoid being in contact with other people who are sick or have infections.
In clinical studies, Actemra showed that when it was given by infusion, whether on its own or with methotrexate, was able to have patients achieve remission. This was after a period of six months, and 45% of patients who took it with methotrexate reported these results, while 39% who took it alone said the same.
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